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meiotic drive

A process occurring during meiosis that results in the two kinds of gametes produced by a heterozygote not being equally common.  It is more often  seen  in  the  formation  of  megaspores than microspores. An example is seen in maize plants that are heterozygous   for   a   chromosome   mutation,   in which one of the homologues of chromosome   10  has  an  abnormal  terminal knob. The knob  acts as  a centromere and causes  the abnormal chromosomes to move to the poles of the spindle earlier in  both  the first and second divisions of meiosis. The product of meiosis is a linear tetrad in which the abnormal chromosomes are more likely to be in the outer two cells. Since all four cells of a tetrad normally develop into pollen grains, the abnormal chromosome is recovered   in   equal   numbers   among   the microspores. However only the basal cell of the  tetrad  develops  into  the  megaspore. Thus the abnormal chromosome is recovered at higher frequencies (about 70%) among the megaspores.

 
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