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histidine

A basic amino acid with the formula C3H3N2CH2CH(NH2)COOH. The occurrence of histidine in proteins is rare. Synthesis is via a complex pathway, starting from the condensation of ATP and 5-phosphoribosyl pyrophosphate, while breakdown is via glutamic acid. In bacteria, the synthesis of histidine has been found to be under genetic control, with histidine acting as its own repressor.

 
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